2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W019773S1
    Albendazole sulfone-d3
    Albendazole sulfone-d3 is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfone-d<sub>3</sub>
  • HY-116617R
    15-Keto Travoprost (Standard)
    Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.
    15-Keto Travoprost (Standard)
  • HY-138094
    N-(2-Hydroxyethyl)oxamic acid
    N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria.
    N-(2-Hydroxyethyl)oxamic acid
  • HY-137316AR
    Phosphoramide mustard cyclohexanamine (Standard)
    Phosphoramide mustard (cyclohexanamine) (Standard) is the analytical standard of Phosphoramide mustard (cyclohexanamine). This product is intended for research and analytical applications. Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].
    Phosphoramide mustard cyclohexanamine (Standard)
  • HY-148376
    Abiraterone N-oxide
    Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity.
    Abiraterone N-oxide
  • HY-12770R
    Mebeverine alcohol (Standard)
    Mebeverine alcohol (Standard) is an analytical standard for Mebeverine alcohol. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of Chloramphenicol (HY-B0239) and Lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis.
    Mebeverine alcohol (Standard)
  • HY-117580R
    16α-Hydroxyprednisolone (Standard)
    16α-Hydroxyprednisolone (OH-PRED) (Standard) is the analytical standard of 16α-Hydroxyprednisolone. This product is intended for research and analytical applications. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily.
    16α-Hydroxyprednisolone (Standard)
  • HY-145949
    Remdesivir de(ethylbutyl 2-aminopropanoate)
    Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
    Remdesivir de(ethylbutyl 2-aminopropanoate)
  • HY-161487
    AOZ/BSA
    AOZ/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    AOZ/BSA
  • HY-116546
    Sch 40853
    Sch 40853 is a active metabolite of SCH 39166 (HY-14690) and can be used for the research of schizophrenia and obesity.
    Sch 40853
  • HY-137117
    15-keto-PGE1
    15-keto-PGE1 is an inactive Prostaglandin E1 (PGE1) metabolite. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation.
    15-keto-PGE1
  • HY-101723R
    Modecainide (Standard)
    Modecainide (Standard) is the analytical standard of Modecainide. This product is intended for research and analytical applications. Modecainide is a major metabolite of Encainide, which is an antiarrhythmic agent.
    Modecainide (Standard)
  • HY-G0003R
    Iloperidone metabolite Hydroxy Iloperidone (Standard)
    Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
    Iloperidone metabolite Hydroxy Iloperidone (Standard)
  • HY-134611
    (2-Hydroxyethoxy)acetic acid
    (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine.
    (2-Hydroxyethoxy)acetic acid
  • HY-131257R
    Gefitinib impurity 1 (Standard)
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.
    Gefitinib impurity 1 (Standard)
  • HY-133980AR
    O-Demethyl Lenvatinib hydrochloride (Standard)
    Bamifylline (hydrochloride) (Standard) is the analytical standard of Bamifylline (hydrochloride). This product is intended for research and analytical applications. Bamifylline hydrochloride is a drug in the chemical class of xanthine that acts as a selective adenosine A1 receptor antagonist.
    O-Demethyl Lenvatinib hydrochloride (Standard)
  • HY-151930S
    8′-Hydroxy ABA-d8
    8′-Hydroxy ABA-d8 is the deuterium labeled 8’-Hydroxy ABA.
    8′-Hydroxy ABA-d<sub>8</sub>
  • HY-N11676
    6-Hydroxy-TSU-68
    6-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68.
    6-Hydroxy-TSU-68
  • HY-N6683R
    15-Acetyl-deoxynivalenol (Standard)
    15-Acetyl-deoxynivalenol (Standard) is the analytical standard of 15-Acetyl-deoxynivalenol. This product is intended for research and analytical applications. 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells.
    15-Acetyl-deoxynivalenol (Standard)
  • HY-113472R
    N-Methyl-4-pyridone-3-carboxamide (Standard)
    3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
    N-Methyl-4-pyridone-3-carboxamide (Standard)
Cat. No. Product Name / Synonyms Application Reactivity